It is a combination
product containing Amlodipine Besylate BP equivalent to 5 mg Amlodipine, a
calcium channel blocker and Atorvastatin Calcium INN equivalent to 10 mg
Atorvastatin, a statin (HMG-CoA reductase inhibitor). Amlodipine is a
peripheral arterial vasodilator that acts directly on vascular smooth muscle to
cause a reduction in peripheral vascular resistance and reduction in blood
pressure. Atorvastatin calcium is a synthetic lipid-lowering agent. It is an
inhibitor of 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA). This enzyme
catalyzes the conversion of HMG-CoA to mevalonate, an early and rate limiting
step in the synthesis of cholesterol.
·
Significant
achievement of both BP and LDL-C goals
·
Significant superior
CHD event reduction
·
Two drugs in one table
to improve convenience and compliance
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